St. Louis Cardinals at Camden Yards, June 28-30, 2011
It's amazing that they're still letting new interleague configurations trickle out more than a decade down the road, but this is the first time the Cardinals have ever played the Baltimore Orioles at Camden Yards. That's interesting in its own right—we have Camden Yards to blame for the proliferation of retro ballparks that eventually invaded St. Louis, and the Orioles, for all their problems, have several exciting young prospects on their roster.
But this is also the Cardinals' first-ever visit to the adopted hometown of their Chuck Cunningham'd brother franchise, the St. Louis Browns. I don't think there are a lot of fans of George Sisler, Ken Williams, or Buster Stephens left, but I get misty-eyed at the thought of them getting misty-eyed at the thought of this 1944 World Series rematch.